Figure 3.

Alignment of the KRTAP15-1 variants identified in goats and sheep. Eight single nucleotide polymorphisms (SNPs) identified in caprine KRTAP15-1 are marked above the sequences, with the non-synonymous SNPs being indicated with the putative amino acid changes and the SNP that would result in an alternative start codon being boxed. Dashes signify homology with the caprine KRTAP15-1*A sequence, with the coding sequence being shown in upper case and the non-coding sequences being shown in lower case. The notional ATG start codon and TAA stop codon are shown in bold. Two putative chi-like sequences are boxed. The primer-binding regions are indicated with horizontal lines. The goat sequences are indicated with a prefix “g”, while the sheep sequences are indicated with a prefix “s”. Numbering of nucleotide and amino acid positions follows the guidelines of the Human Genome Variation Society (HGVS) nomenclature (http://varnomen.hgvs.org/, last access: 21 February 2018). The GenBank accession numbers of these sequences are MH742372 (sKRTAP15-1*A), MH742373 (sKRTAP15-1*B), MH742374 (sKRTAP15-1*C) and MH742375 (sKRTAP15-1*D).