Table 2.
Metabolic characters of rats after 6-month treatment
| Zucker lean, n = 6 | ZDF + Met, n = 7 | ZDF + V, n = 7 | |
|---|---|---|---|
| Body weight (g) | 390 ± 12 | 491 ± 29a | 485 ± 49b |
| 2-h OGTT blood glucose (mmol/L) | 7.9 ± 1.7 | 11.4 ± 2.3ac | 14.7 ± 2.3b |
| Serum total cholesterol (mmol/L) | 1.07 ± 0.07 | 4.9 ± 1.0a | 5.0 ± 0.6b |
| Serum triglyceride (mmol/L) | 0.32 ± 0.02 | 8.9 ± 3.3a | 8.7 ± 1.9b |
| Serum total protein (g/L) | 70.0 ± 1.7 | 70.6 ± 1.7 | 73.0 ± 2.3 |
| Serum albumin (g/L) | 20.7 ± 0.6 | 16.1 ± 2.0a | 15.7 ± 1.4b |
| ALT (U/L) | 79.3 ± 11.4 | 139.9 ± 25.9a | 155.7 ± 79.2b |
| AST (U/L) | 86.7 ± 6.1 | 120.6 ± 22.8a | 156.3 ± 61.0b |
Data are mean ± SD
OGTT oral glucose tolerance test, ALT alanine aminotransferase, AST aspartate transaminase
a,bp < 0.05 versus Zucker lean, c p < 0.05 versus V