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. 2019 Nov 12;19:308. doi: 10.1186/s12906-019-2717-z

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Antimicrobial activity of three distinct fractions C. sylvestris from distinct Brazilian biomes against S. mutans. Data depicted are average and standard deviation. There was statistically significant difference between fraction AcOEt versus vehicle (V) control for all, except PAC/CE (p ≤ 0.0001; two-way ANOVA between the bioma and fraction factors showed that the interaction between the factors is significant by factor p < 0.0001; biome p < 0.0001 and fraction p < 0.0001, followed by the Tukey multiple comparisons test; p > 0.050)