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. 2019 Oct 18;11(3):209–216. doi: 10.2478/intox-2018-0019

Table 4.

Bisphenol A induced changes in phosphatase activity and energy metabolism in cauda epididymis of mice.

Sr. No. Experimental groups Phosphatase activity (ACP) Energy Metabolism
ATPase SDH
Control groups
I Untreated control 0.46±0.06 1.62±0.02 19.21±0.26
II Vehicle control (0.2 ml olive oil/animal/day) 0.45±0.01 1.61±0.01 19.17±0.36
BPA-treated groups
III BPA-Low dose (80 mg/kg bodyweight/day) 0.61±0.01* (58.98) 1.40±0.02* (13.16) 15.33±0.26* (19.96)
IV BPA-Medium dose (120 mg/kg bodyweight/day) 1.00±0.02* (151.862) 1.22±0.02* (24.31) 13.34±0.48* (30.38)
V BPA-High dose (240 mg/kg bodyweight/day) 1.16±0.05* (201.71) 1.07±0.02* (33.80) 1073±0.43* (43.99)

Values are mean±S.E.M., n=10. Values shown in parentheses indicate: Brackets – Percent change in BPA treated from vehicle treated control group. Significance at the level of *p<0.05, as compared with vehicle control,No significant difference was noted between untreated and vehicle control groups. Units: ACP – μmoles p-nitrophenol released/mg protein/30 min; ATPase – μmoles inorganic phosphate released/mg protein/30 min; SDH – μg formazon formed/mg protein/15 min