Table 4.
Groups | Plasma insulin (μIU/ml) level at different periods of time in normal control and STZ-induced diabetic treated rats | ||
---|---|---|---|
At start of therapy | At 22 days of therapy | At the end of therapy (on 45th day) | |
Group 1 | 14.42±0.20 | 15.37±0.18 | 16.19±0.13 |
Group 2 | 14.71±0.15 | 14.67±0.33 | 16.90±0.34 |
Group 3 | 4.18±0.004a | 4.81±0.04a | 10.38±6.65a |
Group 4 | 4.29±0.01 | 4.86±0.18 | 8.5±0.16* |
Group 5 | 4.34±0.02 | 6.79±0.06* | 10.5±0.14** |
Group 6 | 4.49±0.02 | 9.67±0.17** | 13.66±0.17*** |
Group 7 | 4.82±0.07 | 11.42±0.19** | 14.84±0.27*** |
The data are expressed as mean ± SEM. The comparisons were made by one way ANOVA followed by Dunnett’s test.
p<0.05 is considered significant when compared to the control group (0 h)
p<0.001 is considered very significant when compared to the control group (0 h)
p<0.001 is considered extremely significant when compared to the control group (0 h).
a – compared to normal; * – compared to diabetic control