. 2019 Oct 18;11(4):275–288. doi: 10.2478/intox-2018-0027

Table 5.

Effect of HBAO on hepatic gluconeogenic enzymes in normal control and STZ-induced diabetic rats.

Groups	Biochemical estimations of hepatic enzymes
Groups	Glucose-6-phosphate dehydrogenase (units/min/mg of protein)	Glucose-6-phosphatase (units/min/mg of protein)	Fructose-1-6-biphosphatase (units/min/mg of protein)	Hepatic hexokinase (units/min/mg of protein)
Group 1	0.15±0.005	0.03±0.0007	0.01±0.0003	0.24±0.004
Group 2	0.15±0.003	0.03±0.001	0.017±0.0007	0.212±0.003
Group 3	0.04±0.001^a	0.07±0.0003^a	0.07±0.002^a	0.11±0.005^a
Group 4	0.05±0.0008	0.07±0.0005	0.065±0.001	0.13±0.006
Group 5	0.07±0.001	0.18±0.11	0.046±0.001	0.16±0.005
Group 6	0.09±0.002^**	0.04±0.0003^**	0.02±0.001^*	0.20±0.001^**
Group 7	0.12±0.008^***	0.03±0.002^***	0.02±0.001^***	0.21±0.001^***

The data are expressed as mean ± SEM. The comparisons were made by one way ANOVA followed by Dunnett’s test.

p<0.05 is considered significant when compared to the control group (0 h)

^**

p<0.001 is considered very significant when compared to the control group (0 h)

^***

p<0.001 is considered extremely significant when compared to the control group (0 h).

^a – compared to normal; * – compared to diabetic control