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. 2019 Nov 7;52(11):e8333. doi: 10.1590/1414-431X20198333

Table 1. Enriched GO functions and KEGG pathways of differentially expressed coding RNAs.

Category Term Count P value
Biology Process GO: 0009611∼response to wounding 67 2.55E-13
GO: 0006955∼immune response 77 2.08E-12
GO: 0006954∼inflammatory response 44 6.85E-10
GO: 0002684∼positive regulation of immune system process 36 1.67E-09
GO: 0006952∼defense response 64 3.54E-09
GO: 0050778∼positive regulation of immune response 26 1.47E-08
GO: 0002252∼immune effector process 23 2.63E-07
GO: 0045087∼innate immune response 22 1.77E-06
GO: 0048584∼positive regulation of response to stimulus 29 5.96E-06
GO: 0042060∼wound healing 25 1.04E-05
GO: 0001775∼cell activation 32 1.33E-05
GO: 0048534∼hemopoietic or lymphoid organ development 30 1.36E-05
GO: 0030097∼hemopoiesis 28 1.70E-05
GO: 0050865∼regulation of cell activation 23 2.39E-05
GO: 0030029∼actin filament-based process 28 2.49E-05
Cellular Component GO: 0044459∼plasma membrane part 155 2.53E-08
GO: 0031093∼platelet alpha granule lumen 13 2.00E-07
GO: 0005615∼extracellular space 63 2.65E-07
GO: 0044421∼extracellular region part 80 3.03E-07
GO: 0060205∼cytoplasmic membrane-bounded vesicle lumen 13 4.71E-07
GO: 0031983∼vesicle lumen 13 7.98E-07
GO: 0031091∼platelet alpha granule 14 1.19E-06
GO: 0042611∼MHC protein complex 14 1.48E-06
GO: 0005886∼plasma membrane 226 3.93E-06
GO: 0005576∼extracellular region 135 4.08E-06
GO: 0005887∼integral to plasma membrane 89 5.27E-06
GO: 0031226∼intrinsic to plasma membrane 90 7.08E-06
Molecular Function GO: 0004857∼enzyme inhibitor activity 35 1.04E-07
GO: 0003779∼actin binding 36 3.10E-06
GO: 0004866∼endopeptidase inhibitor activity 22 3.18E-06
GO: 0030414∼peptidase inhibitor activity 22 7.56E-06
GO: 0032395∼MHC class II receptor activity 8 1.36E-05
KEGG Pathway hsa04610: Complement and coagulation cascades 18 2.04E-07
hsa05330: Allograft rejection 12 2.50E-06
hsa04514: Cell adhesion molecules (CAMs) 22 1.69E-05
hsa04612: Antigen processing and presentation 15 0.000189
hsa04810: Regulation of actin cytoskeleton 23 0.004886
hsa04670: Leukocyte transendothelial migration 15 0.00551
hsa04650: Natural killer cell mediated cytotoxicity 16 0.006762
hsa04666: Fc gamma R-mediated phagocytosis 12 0.013475
hsa04662: B cell receptor signaling pathway 10 0.017701
hsa03320: PPAR signaling pathway 9 0.027244
hsa04062: Chemokine signaling pathway 18 0.028853
hsa04540: Gap junction 10 0.043395
hsa04520: Adherens junction 9 0.04559
hsa04142: Lysosome 12 0.046965
hsa04510: Focal adhesion 18 0.048777

GO: Gene Ontology.