Table 1.
Composition of the BA mixtures and the concentrations of the individual BAs found within each mixture. In order to create a dose-response, the concentrations of the individual BAs were increased to reach a supra-physiological 1000 x BA mix.
| Bile acid | Concentration in 1 x BA (μM) | Concentration in 10 x BA (μM) | Concentration in 100 x BA (μM) | Concentration in 1000 x BA (μM) |
|---|---|---|---|---|
| Cholic acid | 0.41 | 4.1 | 41 | 410 |
| Chenodeoxycholic acid | 0.64 | 6.4 | 64 | 640 |
| Deoxycholic acid | 0.48 | 4.8 | 48 | 480 |
| Lithocholic acid | 0.008 | 0.08 | 0.8 | 8 |
| Ursodeoxycholic acid | 0.14 | 1.4 | 14 | 140 |
| Glycochenodeoxycholic acid | 0.8 | 8 | 80 | 800 |
| Sum | 2.478 | 24.78 | 247.8 | 2478 |