Fig. 2.

Summary of the principle underlying inflammatory mechanisms and subsequent clinical manifestations affecting atherosclerosis, aortic aneurysm formation and aortitis. eNOS = endothelial nitric oxide synthase, INF = interferon, IL = Interleukin, LDL = low density lipoprotein, MMP = Matrix metalloproteinase, NK = natural killer, NF-KB = nuclear factor kappa-light-chain-enhancer of activated B cells, ox = oxidized, ROS = reactive oxygen species, PDGF = platelet derived growth factor, SMC = smooth muscle cell, Th = T-helper, TNF = Tumour necrosis factor, VEGF = vascular endothelial growth factor. Images adapted fromhttps://smart.servier.com(Servier Medical Art by Servier) used under a creative commons license.