Table 2.

Oncomine (https://www.oncomine.org) gene analysis comparing the expression of fatty acid desaturases (FADS1 and FADS2) in patient samples collected from metastatic or primary sites across all cancers. Leukemia and multiple myeloma samples were compared to normal bone marrow. Data were ordered by “overexpression,” and the threshold was adjusted to P value < 1E4; fold change, 2; and gene rank, top 10%

Gene	Fold change	P value	Dataset	Analysis
FADS1	1.335	5.84E–7	Yu prostate	Metastasis vs. primary
	1.953	3.31E–5	Grasso prostate	Metastasis vs. primary
	1.353	0.002	Lapointe prostate	Metastasis vs. primary
	1.343	0.003	Bittner colon	Metastasis vs. primary
	1.124	0.006	Chen gastric	Metastasis vs. primary
	1.164	0.008	Bittner ovarian	Metastasis vs. primary
	1.307	0.010	Linn sarcoma	Metastasis vs. primary
	1.201	0.024	Graudens colon	Metastasis vs. primary
	1.447	0.025	Holzbeierlein prostate	Metastasis vs. primary
	2.593	0.034	Varambally prostate	Metastasis vs. primary
	1.807	0.037	Bittner lung	Metastasis vs. primary
	1.570	0.040	Segal sarcoma	Metastasis vs. primary
	1.508	0.042	Adib ovarian	Metastasis vs. primary
	2.022	0.064	Segal sarcoma 2	Metastasis vs. primary
	1.119	0.068	Jones renal	Metastasis vs. primary
	3.378	0.082	Ramaswamy multi-cancer 2	Metastasis vs. primary
	2.831	0.092	Ramaswamy multi-cancer	Metastasis vs. primary
	2.066	2.11E–57	Haferlach leukemia	T cell ALL vs. normal
	1.459	4.32E–36	Haferlach leukemia	B cell childhood ALL vs. normal
	1.427	8.31E–34	Haferlach leukemia	AML vs. normal
	1.444	1.36E–28	Haferlach leukemia	B cell ALL vs. normal
	1.170	3.05E–4	Haferlach leukemia	CML vs. normal
FADS2	1.673	3.24E–6	Linn sarcoma	Metastasis vs. primary
	1.377	1.12E–5	Chandran prostate	Metastasis vs. primary
	1.357	0.011	Jones renal	Metastasis vs. primary
	1.399	0.016	Bittner colon	Metastasis vs. primary
	2.604	0.037	Varambally prostate	Metastasis vs. primary
	1.409	0.050	Lapointe prostate	Metastasis vs. primary
	1.204	0.050	Bittner ovarian	Metastasis vs. primary
	2.151	0.081	Liao liver	Metastasis vs. primary
	1.363	0.098	Holzbeierlein prostate	Metastasis vs. primary
	1.490	1.22E–12	Haferlach leukemia	T cell ALL vs. normal
	1.118	0.007	Haferlach leukemia	AML vs. normal
	1.097	0.058	Haferlach leukemia	CML vs. normal
	4.258	1.84E–5	Andersson leukemia	T cell ALL vs. normal
	1.746	0.010	Andersson leukemia	AML vs. normal
	1.503	0.027	Andersson leukemia	B cell ALL vs. normal
	1.425	0.002	Maia leukemia	B cell ALL vs. normal
	2.522	0.004	Zhan myeloma 3	Smoldering myeloma vs. normal