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(A) Western blot for MeCP2 in whole liver or activated HSCs; MeCP2 WT and KO brain was used as positive or negative control, respectively. (B) Liver–to–body weight ratio in WT and MeCP2S80A mice treated with chronic CCl4 or vehicle. Error bars in relevant panels represent mean ± SEM. ***P < .001. (C) Assessment of serum transaminases alanine transaminase (ALT) and aspartate transaminase (AST). KO, knockout.
