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. 2019 Dec 1;140:105068. doi: 10.1016/j.ejps.2019.105068

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© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 1 — Predicted vs Observed plasma concentration-time profile of efavirenz and thalidomide in adults. A - Observed (mean) reported by Villani et al. (1999) and Predicted (mean & SD) plasma concentration-time profile of 600 mg efavirenz at steady-state in adults; and B - Observed (mean) reported by Piscitelli et al. (1997) and Predicted (mean & SD) plasma concentration-time profile of 100 mg thalidomide after single-dose in adults; and C - Observed (mean) reported by Piscitelli et al. (1997) and Predicted (mean & SD) plasma concentration-time profile of 300 mg thalidomide after single-dose in adults.