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. Author manuscript; available in PMC: 2019 Nov 13.
Published in final edited form as: Stem Cell Res. 2019 Aug 7;40:101529. doi: 10.1016/j.scr.2019.101529

Figure 4. Editing of the expanded GAAs partially corrects FRDA transcriptome.

Figure 4

(A) Venn diagram illustrating the comparison of differentially expressed genes between PCm and ECm cells (p<0.01) with genes differentially expressed between CCm and PCm cells (p<0.01). (B) A heatmap illustrating expression of the 1764 genes differentially expressed in both groups (PCm/ECm and PCm/CCm; Supplemental Table 3). (C) PANTHER pathways analysis of genes downregulated and upregulated in PCm versus CCm cells (p<0.05).