Table 2. Samples collected and analyzed with 16S rDNA ddPCR and species-specific ddPCR in 83 patients with Staphylococcus aureus, Streptococcus pneumoniae, or Escherichia coli bloodstream infection.
| Results | Numbers (% of analyzed samples) | ||||
|---|---|---|---|---|---|
| Day 0 | Days 1–2 | Days 3–4 | Days 6–8 | Days 13–15 | |
| All patients (n = 83) | |||||
| Samples collected | 30 | 72 | 55 | 65 | 56 |
| Samples analyzed | 30 | 63 | 35 | 21 | 8 |
| 16S rDNA ddPCR + | 18 (60) | 35 (56) | 16 (46) | 8 (38) | 4 (50) |
| Species-specific ddPCR + | 21 (70) | 34 (54) | 16 (46) | 4 (19) | 0 |
| S. aureus BSI patients (n = 27) | |||||
| Samples collected | 7 | 24 | 20 | 24 | 17 |
| Samples analyzed | 7 | 24 | 18 | 13 | 6 |
| 16s rDNA ddPCR + | 7 (100) | 18 (75) | 13 (72) | 8 (62) | 4 (67) |
| nuc ddPCR + | 7 (100) | 19 (79) | 10 (56) | 3 (23) | 0 |
| S. pneumoniae BSI patients (n = 30) | |||||
| Samples collected | 9 | 28 | 15 | 25 | 25 |
| Samples analyzed | 9 | 28 | 7 | 3 | 1 |
| 16S rDNA ddPCR + | 4 (44) | 11 (39) | 2 (29) | 0 | 0 |
| lytA ddPCR + | 5 (56) | 9 (32) | 0 | 1 (33) | 0 |
| E. coli BSI patients (n = 26) | |||||
| Samples collected | 14 | 20 | 20 | 16 | 14 |
| Samples analyzed | 14 | 11 | 10 | 5 | 1 |
| 16S rDNA ddPCR + | 7 (50) | 4 (36) | 2 (20) | 0 | 0 |
| uidA ddPCR + | 9 (64) | 6 (55) | 6 (60) | 0 | 0 |