Table 1. Immunoaffinity purification and identification of FH-NPM and FH-NPM-MLF1 interacting proteins from K562 cells, by LC-MS/MS analysis.
| NPM associated factors | |||||
| Gene symbol | Nb unique peptides | Nb peptides total | AVG | Coverage | Complex |
| NPM | 49 | 704 | 3.4781 | 72.4% | - |
| HDAC1 | 1 | 2 | 2.7785 | 2.5% | NuRD |
| MTA1 | 1 | 1 | 1.5869 | 1.4% | NuRD |
| GATAD2A | 2 | 2 | 2.7539 | 3.6% | NuRD |
| SMARCC1 (BAF155) | 13 | 13 | 2.4901 | 12.4% | P/BAF |
| SMARCC2 (BAF170) | 5 | 5 | 2.7647 | 5.4% | P/BAF |
| ACTL6A | 3 | 3 | 3.2014 | 10.7% | P/BAF |
| SMARCB1 (SNF5) | 2 | 2 | 2.8289 | 7.8% | P/BAF |
| SMARCD2 (BAF60B) | 2 | 2 | 3.3591 | 5.3% | P/BAF |
| SMARCD1 (BAF60A) | 1 | 1 | 3.407 | 2.5% | P/BAF |
| SMARCA4 (BRG1) | 1 | 1 | 2.6197 | 0.7% | P/BAF |
| BAF180 (PBRM1) | 1 | 1 | 3.6717 | 1.1% | P/BAF |
| DDX21 | 27 | 34 | 3.0167 | 35% | ISWI |
| SMARCA5 (SNF2H) | 23 | 26 | 2.7362 | 22.2% | ISWI |
| SMARCA1 (SNF2L) | 9 | 9 | 2.6112 | 5.8% | ISWI |
| MYBBP1A | 7 | 7 | 2.6662 | 5.3% | ISWI |
| WSTF (BAZ1B) | 5 | 5 | 2.4308 | 4.4% | ISWI |
| DEK | 2 | 2 | 2.7281 | 8.3% | ISWI |
| NPM-MLF1 associated factors | |||||
| Gene symbol | Nb unique peptides | Nb peptides total | AVG | Coverage | Complex |
| NPM | 30 | 202 | 3.3753 | 68% | - |
| CHD4 | 19 | 24 | 2.7103 | 9.7% | NuRD |
| HDAC1 | 12 | 13 | 2.8632 | 23.7% | NuRD |
| HDAC2 | 8 | 9 | 3.2925 | 14.5% | NuRD |
| RBBP4 | 8 | 9 | 2.8428 | 26.1% | NuRD |
| CHD3 | 7 | 8 | 2.8151 | 4.5% | NuRD |
| GATAD2A | 5 | 5 | 2.7687 | 10.4% | NuRD |
| MTA2 | 4 | 5 | 3.166 | 8.8% | NuRD |
| MTA1 | 3 | 3 | 2.8883 | 4.9% | NuRD |
| MBD3 | 1 | 1 | 3.1199 | 4.8% | NuRD |
| GATAD2B | 1 | 1 | 3.4446 | 4.2% | NuRD |
| BAF180 (PBRM1) | 27 | 29 | 2.771 | 18.2% | P/BAF |
| SMARCC1 (BAF155) | 13 | 14 | 2.8801 | 16.8% | P/BAF |
| SMARCA2 (BRM) | 8 | 9 | 2.6807 | 6% | P/BAF |
| SMARCA4 (BRG1) | 8 | 8 | 3.0084 | 6.4% | P/BAF |
| ARID2 | 7 | 7 | 2.7209 | 6.9% | P/BAF |
| SMARCC2 (BAF170) | 6 | 6 | 3.615 | 7.4% | P/BAF |
| ACTL6A | 3 | 3 | 3.1549 | 8.6% | P/BAF |
| BRD7 | 3 | 3 | 3.5831 | 9.8% | P/BAF |
| SMARCB1 (SNF5) | 1 | 1 | 3.3006 | 3.6% | P/BAF |
| SMARCD1 (BAF60A) | 1 | 1 | 2.9127 | 2.5% | P/BAF |
| SMARCE1 (BAF57) | 1 | 1 | 3.303 | 2.9% | P/BAF |
| SMARCD2 (BAF60B) | 1 | 1 | 3.2464 | 2.8% | P/BAF |
| SMARCE1 | 1 | 1 | 3.303 | 2.9% | P/BAF |
| BAF45A (PHF10) | 1 | 1 | 2.4624 | 3.6% | P/BAF |
| BCL7C | 1 | 1 | 2.2226 | 5.5% | P/BAF |
| BCL7A | 1 | 1 | 1.8993 | 4.8% | P/BAF |
| SMARCA5 (SNF2H) | 19 | 20 | 3.0813 | 18.5% | ISWI |
| BPTF | 12 | 12 | 3.0648 | 5.6% | ISWI |
| SMARCA1 (SNF2L) | 10 | 11 | 2.2798 | 7.5% | ISWI |
| DDX21 | 9 | 10 | 2.8947 | 15.1% | ISWI |
| WSTF (BAZ1B) | 7 | 8 | 3.0102 | 7.1% | ISWI |
| MYBBP1A | 2 | 2 | 2.7507 | 1.9% | ISWI |
Gene symbols, number of unique and total peptides, corresponding average mass (AVG), percentage of coverage and known protein complexes are indicated. P/BAF: BAF and PBAF complexes.