Table 4. ARDS 8 values of gas exchange, EIT- indices, respiratory mechanics and hemodynamics.
| LPS group | LAV group | CO group | p-value (LPS vs LAV) | p-value (LPS vs CO) | p-value (LAV vs CO) | |
|---|---|---|---|---|---|---|
| GI index | 25.5 (25.1–28.4) |
27.8 (25.7–29.1) |
26.6 (25.5–27.1) |
0.421 | 0.690 | 0.421 |
| RVD index | 5.3 (3.3–6.2) |
6.9 (5.4–11.2) |
4.3 (3.6–5.8) |
0.082 | 0.792 | 0.056 |
| Compliance, ml/mbar | 12.4 (10.7–13.4) |
7.4 (6.9–11.8) |
17.6 (16.1–17.9) |
0.052 | 0.004* | 0.008* |
| PIP, mbar | 27 (26–29) |
38 (29–39) |
21 (20–22) |
0.017* | 0.004* | 0.008* |
| RR, /min | 35 (32–35) |
38 (27–38) |
25 (24–28) |
0.662 | 0.004* | 0.056 |
| Horowitz Index | 104 (56–131) |
143 (70–287) |
476 (447–519) |
0.329 | 0.004* | 0.008* |
| SAP, mmHg | 99 (88–109) |
114 (110–128) |
126 (116–135) |
0.017* | 0.004* | 0.222 |
| SPAP, mmHg | 36 (34–42) |
41 (39–52) |
32 (30–34) |
0.151 | 0.032* | 0.008* |
| HR, /min | 193 (154–202) |
90 (80–138) |
78 (76–111) |
0.017* | 0.004* | 0.421 |
| Cardiac output, l/min | 4.2 (2.8–5.0) |
3.4 (2.9–3.9) |
3.3 (3.0–3.8) |
0.421 | 0.548 | 0.917 |
| Lactate, mmol | 1.6 (1.5–3.6) |
0.4 (0.3–0.6) |
0.5 (0.5–0.6) |
0.004* | 0.004* | 0.310 |
| Total balanced crystalloid solution, ml | 5300 (4563–6325) |
4100 (3825–4600) |
3900 (3600–4350) |
0.052 | 0.017* | 0.548 |
| Total urine output, ml | 550 (450–838) |
2000 (1300–3400) |
1150 (900–1600) |
0.004* | 0.009* | 0.095 |
Abbreviations: GI index = global inhomogeneity index, RVD index = regional ventilation delay index, PIP = Peak Inspiratory Pressure; RR = Respiratory Rate; SAP = Systolic arterial pressure; SPAP = Systolic pulmonary arterial pressure; HR = Heart Rate; LPS group = Lipopolysaccharide group; LAV group = Lavage group; CO group = Control group, ARDS 8 = Eight hours after ARDS
* = p<0.05