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. Author manuscript; available in PMC: 2020 Apr 8.
Published in final edited form as: ACS Biomater Sci Eng. 2019 Mar 8;5(4):1937–1943. doi: 10.1021/acsbiomaterials.8b01356

Figure 5. Organoid and TCP Chemotherapy Screening.

Figure 5.

Cell from the 7-23-17 sample (A) and H460 PE-derived lung adenocarcinoma cells (B) were cultured in organoids for 5 weeks and in TCP and then treated with the indicated chemotherapy drugs for 3 days. MTS assay was carried out to determine cell viability and results were normalized to untreated cells (Control). Some of the organoids made with H460 cells contained in addition normal human lung fibroblasts (NHLF) (* p<0.05, ** p<0.005) (+ p<0.05, ++ p<0.005 with control).