Time to hospital discharge (intention-to-treat population) in adults and children with severe influenza-like illness. Adult population: nitazoxanide (NTZ) + standard of care (SOC) (n = 63): Kaplan-Meier estimate of the median (8.0 [interquartile range {IQR}, 6.0–11.0]) vs placebo + SOC (n = 63): Kaplan-Meier estimate of the median (8.0 [IQR, 6.0–10.0]); Fay-Shaw formulation of the rank-sum statistic, P = .62. Child population: NTZ + SOC (n = 67): Kaplan-Meier estimate of the median (5.0 [IQR, 3.0–7.0]) vs placebo + SOC (n = 64): Kaplan-Meier estimate of the median (5.0 [IQR, 4.0–8.0]); Fay-Shaw formulation of the rank-sum statistic, P = .30.