Table 2.
DEGs Also Found To Be Differentially Expressed in the Testis of Neonatal Mice With a Dominant-Negative Mutation of THRA
| Gene | FC in Mutant THRA | FC in Dio3KO | Direction of Regulation | Gene | FC in Mutant THRA | FC in Dio3KO | Direction of Regulation |
|---|---|---|---|---|---|---|---|
| 1810041L15Rik | 2.56 | 1.636364 | Up | Itgb2 | 2.51 | 1.55814 | Up |
| 2310046K01Rik | 0.49 | 2.002799 | Opposite | Jakmip1 | 0.45 | 2.274603 | Opposite |
| Abcb1b | 2.31 | 1.776699 | Up | Laptm5 | 2.19 | 2.274787 | Up |
| Alox5 | 2.33 | 1.617647 | Up | Lpar3 | 0.35 | 7.717241 | Opposite |
| Alox5ap | 2.15 | 1.761236 | Up | Mmp9 | 2.72 | 0.5390946 | Opposite |
| Bik | 0.44 | 1.850829 | Opposite | Msr1 | 2.71 | 2.212121 | Up |
| Cfh | 2.24 | 2.220697 | Up | Nfam1 | 2.1 | 1.75 | Up |
| Cldn11 | 0.44 | 3.586293 | Opposite | Parvb | 2.19 | 2.93617 | Up |
| Cttnbp2 | 2.22 | 2.22973 | Up | Rtl1 | 2.69 | 0.7285068 | Opposite |
| F5 | 2.41 | 1.722222 | Up | Serpinb2 | 2.19 | 1.826087 | Up |
| Foxq1 | 0.48 | 1.883895 | Opposite | Slc38a3 | 2.15 | 2.108696 | Up |
| Gata1 | 0.47 | 1.890173 | Opposite | Slc47a2 | 0.47 | 2.388493 | Opposite |
| Gda | 2.41 | 3.052632 | Up | Spinlw1 | 0.47 | 1.8577 | Opposite |
| Glis3 | 0.48 | 0.7026144 | Down | Srgn | 2.16 | 1.608333 | Up |
| Gm14492 | 2.09 | 0.6179775 | Opposite | Sycp3 | 0.45 | 1.434726 | Opposite |
| Gm4349 | 2.04 | 0.7612613 | Opposite | T | 2.79 | 0.5217391 | Opposite |
| H2-Q10 | 0.35 | 3.895189 | Opposite | Tbc1d30 | 0.46 | 1.701699 | Opposite |
| Hoxa9 | 2.1 | 2.576923 | Up | Tmsb15l | 0.45 | 0.7870553 | Down |
| Hrk | 0.49 | 5.71223 | Opposite | Tubb2a-ps2 | 2.03 | 0.3781095 | Opposite |
| Itgam | 4.61 | 1.690909 | Up |
Abbreviation: FC, fold change.
[From: Chatonnet F, Livera G, Fumel B, Fouch ES, Flamant F. Direct and indirect consequences on gene expression of a thyroid hormone receptor alpha 1 mutation restricted to Sertoli cells. Mol Reprod Dev 2014;81:1159–1166.]