Table 2. Local status of oral mucosa in patients receiving chemotherapy and treated by Lysobact Complete Spray or compounded medication.
| Lysobact (N=54) | Compounded medication (N=35) | p - value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| The check-up time | Before the treatment | 7th day | 14th day | 21st day | Before the treatment | 7th day | 14th day | 21st day | |
| Lips | |||||||||
| Normal finding (%) | 57.4 | 61.1 | 84.9 | 96.1 | 48.6 | 48.6 | 64.7 | 81.3 | 0.004 |
| Hypersensitivity/erythema (%) | 25.9 | 33.3 | 11.3 | 0 | 48.6 | 51.4 | 35.3 | 18.8 | |
| Erythema/ulcers (%) | 7.4 | 5.6 | 3.8 | 3.9 | 2.9 | 0 | 0 | 0 | |
| Ulcers (%) | 9.3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Cheeks | |||||||||
| Normal finding (%) | 33.3 | 55.6 | 86.8 | 94,1 | 14.3 | 20.0 | 55.9 | 71.9 | 0.001 |
| Hypersensitivity/erythema (%) | 31.5 | 38.9 | 9.4 | 0 | 48.6 | 68.6 | 41.2 | 25.0 | |
| Erythema/ulcers (%) | 14.8 | 3.7 | 3.8 | 5,9 | 28.6 | 8.6 | 2.9 | 3.1 | |
| Ulcers (%) | 20.4 | 1.9 | 0 | 0 | 8.6 | 2.9 | 0 | 0 | |
| Tongue | |||||||||
| Normal finding (%) | 40.7 | 64.8 | 79.2 | 96,0 | 31.4 | 34.3 | 52.9 | 56.3 | 0.001 |
| Hypersensitivity/erythema (%) | 38.9 | 31.5 | 17 | 0 | 31.4 | 65.7 | 47.1 | 43.8 | |
| Erythema/ulcers (%) | 7.4 | 1.9 | 3.8 | 4,0 | 31.4 | 0 | 0 | 0 | |
| Ulcers (%) | 13.0 | 1.9 | 0 | 0 | 5.7 | 0 | 0 | 0 | |
| Palate | |||||||||
| Normal finding (%) | 38.9 | 55.6 | 77.4 | 92,2 | 20.0 | 88.6 | 50 | 50.0 | 0.001 |
| Hypersensitivity/erythema (%) | 20.4 | 31.5 | 17.0 | 3,9 | 40.0 | 60.0 | 44.1 | 46.9 | |
| Erythema/ulcers (%) | 22.2 | 11.1 | 5.7 | 3,9 | 28.6 | 5.7 | 5.9 | 3.1 | |
| Ulcers (%) | 18.5 | 1.9 | 0 | 0 | 11.4 | 5.7 | 0 | 0 | |