Table 4. Local status of oral mucosa in patients on radiotherapy and treated by Lysobact Complete Spray or compounded medication.
| Lysobact Complete Spray (N=50) | Compounded medication (N=50) | p - value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| The check-up time | Before the treatment | 7th day | 14th day | 21st day | Before the treatment | 7th day | 14th day | 21st day | |
| Lips | |||||||||
| Normal finding (%) | 58.0 | 60.0 | 64.0 | 72.0 | 62,0 | 56.0 | 40.0 | 52.0 | 0.210 |
| Hypersensitivity/erythema (%) | 16.0 | 20.0 | 18.0 | 20.0 | 26,0 | 30.0 | 46.0 | 36.0 | |
| Erythema/ulcers (%) | 14.0 | 14,0 | 18.0 | 6.0 | 10,0 | 10.0 | 10.0 | 10.0 | |
| Ulcers (%) | 12.0 | 6.0 | 0.0 | 2.0 | 2,0 | 4.0 | 4,0 | 2.0 | |
| Cheeks | |||||||||
| Normal finding (%) | 20.0 | 26.0 | 36.0 | 42.0 | 14,0 | 14.0 | 16.0 | 26.0 | 0.027 |
| Hypersensitivity/erythema (%) | 32.0 | 22.0 | 24.0 | 42.0 | 48,0 | 42.0 | 38.0 | 38.0 | |
| Erythema/ulcers (%) | 30.0 | 32.0 | 34.0 | 6.0 | 26,0 | 34,0 | 42.0 | 28.0 | |
| Ulcers (%) | 18.0 | 20.0 | 6.0 | 10.0 | 12,0 | 10.0 | 4.0 | 8.0 | |
| Tongue | |||||||||
| Normal finding (%) | 10.0 | 4.0 | 18.0 | 32.0 | 0,0 | 0.0 | 4.0 | 16.0 | 0.110 |
| Hypersensitivity/erythema (%) | 30.0 | 14.0 | 28.0 | 38.0 | 50,0 | 32.0 | 26.0 | 32.0 | |
| Erythema/ulcers (%) | 34,0 | 54.0 | 44.0 | 20.0 | 34,0 | 44.0 | 46.0 | 34.0 | |
| Ulcers (%) | 26.0 | 28.0 | 10.0 | 10.0 | 16,0 | 24.0 | 24.0 | 18.0 | |
| Palate | |||||||||
| Normal finding (%) | 36.0 | 30.0 | 48.0 | 64.0 | 38,0 | 28.0 | 26.0 | 32.0 | 0.013 |
| Hypersensitivity/erythema (%) | 14.0 | 20.0 | 24.0 | 28.0 | 36,0 | 32.0 | 42.0 | 46.0 | |
| Erythema/ulcers (%) | 28.0 | 32.0 | 20.0 | 6.0 | 12,0 | 24.0 | 20.0 | 16.0 | |
| Ulcers (%) | 22.0 | 18.0 | 8.0 | 2.0 | 14,0 | 16.0 | 12.0 | 6.0 | |