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. 2019 Sep 27;8(16):7055–7064. doi: 10.1002/cam4.2569

Figure 2.

Figure 2

SOX2 is a direct transcriptional suppressor of the Hippo regulator WWC1. (A‐B) Trace from SOX2 (A) and p63 (B) ChIP‐seq data in ESCC cell line TT showing binding peaks around the indicated genes. (C) Correlation between SOX2 and WWC1, YAP1, and NF2 in SCC samples from the TCGA Esophageal Cancer (ESCA). (D) Correlation between ACTL6A, TP63, and WWC1 in SCC samples from ESCA dataset