Table 2.
Expression levels of the five plasma miRNAs in the training and testing sets; presented as mean ± SD
| miRNA | Training set | Testing set | Combined | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BC | HC | FC | P value | BC | HC | FC | P value | FDR | FC | P value | |
| let‐7b‐5p | 3.82 ± 2.01 | 4.81 ± 1.44 | 1.98 | .001 | 4.52 ± 0.81 | 6.11 ± 0.63 | 3.03 | <.001 | <0.001 | 2.56 | <.001 |
| miR‐122‐5p | 4.00 ± 2.44 | 4.86 ± 1.61 | 1.82 | .042 | 5.42 ± 1.12 | 6.50 ± 0.68 | 2.11 | <.001 | <0.001 | 1.99 | <.001 |
| miR‐146b‐5p | 8.45 ± 2.62 | 9.47 ± 1.37 | 2.02 | .045 | 10.34 ± 0.92 | 10.99 ± 0.63 | 1.57 | <.001 | <0.001 | 1.73 | <.001 |
| miR‐210‐3p | 4.63 ± 2.77 | 5.63 ± 2.05 | 2.01 | .036 | 6.44 ± 1.18 | 7.03 ± 0.92 | 1.50 | <.001 | <0.001 | 1.68 | <.001 |
| miR‐215‐5p | 3.95 ± 3.19 | 5.16 ± 2.15 | 2.31 | .042 | 5.69 ± 1.36 | 6.49 ± 1.11 | 1.74 | <.001 | <0.001 | 1.94 | <.001 |
Abbreviations: ΔCT, relative to combination of cel‐miR‐39 and miR‐16; FC, fold change; FDR, false discovery rate.