Table 1.

Immunohistochemical features of EGGCTs

Histotype	CK	αFP	βhCG	CD117	PLAP	CD30	OCT4	SALL4	Glypican 3	NANOG	LIN28	SOX2
SE	Nega	Neg	Negb	Pos	Pos	Neg	Pos	Pos	Neg	Pos	Pos	Neg
EC	Pos	Neg/Pos	Negb	Neg	Neg	Pos	Pos	Pos	Neg/Pos	Pos	Pos/Neg	Pos
YSC	Pos	Pos	Negb	Neg	Neg/Pos	Neg/Pos	Neg	Pos	Pos	Neg	Neg	Neg
PT	Pos	Neg	Neg	Neg	Neg	Neg	Neg	Neg	Neg	Neg	Neg	Neg
CHC	Pos	Neg	Pos	Neg	Neg	Neg	Neg	Posc	Pos	Neg	Neg	Neg/Pos

Abbreviations: αFP, alpha fetoprotein; β‐hCG, beta human chorionic gonadotropin; CHC, choriocarcinoma; EC, embryonal carcinoma; PT, pure teratoma; SE, seminoma; YSC, yolk sac tumor.

^aDot‐like positivity can be observed.

^bSyncytiotrophoblastic cells are positive, if present.

^cPositive in mononuclear trophoblastic cells.