Table 4.
Variables | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
OR (95%CI) | p | OR (95%CI) | p | |
Age at operation (years) | 0.91 (0.88, 0.95) | 0.001 | 0.91 (0.87, 0.95) | <0.001 |
Weight (kg) | 0.97 (0.95, 0.99) | 0.001 | ||
Body surface area (m2) | 0.29 (0.15, 0.59) | 0.001 | ||
Glenn surgery history (yes vs. no) | 1.44 (0.96, 2.17) | 0.074 | ||
Surgeons (senior vs. junior) | 1.43 (0.95, 2.15) | 0.081 | ||
Original anatomy (Unbalanced AVSD as Ref.) |
||||
Tricuspid atresia | 0.52 (0.29, 0.94) | 0.03 | ||
Unbalanced DORV | 0.9 (0.51, 1.57) | 0.703 | ||
Double inlet ventricle | 0.45 (0.2, 1.05) | 0.065 | ||
Pulmonary atresia | 1.7 (0.84, 3.46) | 0.139 | ||
TGA | 1.01 (0.41, 2.5) | 0.983 | ||
CCTGA | 1.14 (0.53, 2.42) | 0.74 | ||
Others | 0.91 (0.27, 3.06) | 0.878 | ||
Main ventricle ejection fraction (>55% vs. ≤55%) | 0.8 (0.46, 1.18) | 0.15 | ||
Preoperative lymphocyte (× 109/L) | 1.1 (0.98, 1.24) | 0.102 | ||
Preoperative hemoglobin (g/dL) | 0.9 (0.84, 0.97) | 0.003 | ||
Preoperative platelet (× 1010/L) | 1.04 (1.02, 1.06) | 0.001 | ||
Preoperative prothrombin time (s) | 0.89 (0.77, 1.02) | 0.084 | ||
Preoperative alamine aminotransferase (U/L) | 0.97 (0.95, 0.998) | 0.028 | ||
Preoperative aspartate aminotransferase (U/L) | 1.03 (1.01, 1.05) | 0.01 | ||
Preoperative CKMB (U/L) | 1.02 (1.01, 1.03) | 0.038 | ||
Creaction of fenestraion | 0.43 (0.29, 0.64) | 0.001 | 0.51 (0.33, 0.79) | 0.003 |
Maximal VIS during surgery | 1.03 (1.01, 1.05) | 0.027 | ||
Intraoperative fluid balance (mL/kg) | 1.01 (0.98, 1.013) | 0.075 | ||
Lactic acid (mmol/L) | 1.1 (0.98, 1.25) | 0.113 | ||
Postoperative lymphocyte (× 109/L) | 1.44 (1.11, 1.87) | 0.007 | ||
Postoperative hemoglobin (g/dL) | 0.92 (0.85, 0.99) | 0.021 | ||
Postoperative platelet (× 1010/L) | 1.01 (1.002, 1.03) | 0.084 | ||
Postoperative prothrombin time (s) | 1.09 (1.02, 1.17) | 0.005 | ||
Postoperative total protein (g/L) | 0.96 (0.94, 0.98) | 0.001 | 0.96 (0.93, 0.99) | 0.024 |
Postoperative albumin (g/L) | 0.97 (0.94, 0.997) | 0.044 | ||
Postoperative alamine aminotransferase (U/L) | 1.0008 (1.0002, 1.0015) | 0.003 | ||
Postoperative aspartate aminotransferase (U/L) | 1.0007 (1.0002, 1.0013) | 0.001 | ||
Postoperative TBIL (≥38 vs. <38 μmol/L) | 0.72 (0.49, 1.06) | 0.093 | ||
Postoperative lactate dehydrogenase (U/L) | 1.0006 (1.0002, 1.001) | 0.002 | ||
Postoperative high-sensitivity C-reactive protein (mg/L) |
0.95 (0.89, 1.02) | 0.137 | ||
Postoperative fluid balance (mL/kg) | 1.0036 (0.9993, 1.008) | 0.072 | ||
Postoperative mechanical ventilation (≥48 vs. <48 h) | 2.66 (1.58, 4.46) | 0.001 | 2.52 (1.35, 4.73) | 0.004 |
Chylothorax (yes vs. no) | 2.95 (1.98, 4.41) | 0.001 | 2.6 (1.7, 3.98) | <0.001 |
OR, odds ratios; AVSD, atrioventricular septal defect; DORV, double outlet right ventricle; TGA, complete transposition of great arteries; CCTGA, congenitally corrected transposition of the great arteries; CKMB, isoenzyme of creatine kinase-MB; VIS, maximum vasoactive-Inotropic score during surgery; TBIL, total bilirubin. Bold values mean statistical p < 0.05.