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. 2019 Nov 7;7:456. doi: 10.3389/fped.2019.00456

Table 4.

Univariate and multivariate logistic analysis odds ratios for prolonged pleural effusion.

Variables Univariate analysis Multivariate analysis
OR (95%CI) p OR (95%CI) p
Age at operation (years) 0.91 (0.88, 0.95) 0.001 0.91 (0.87, 0.95) <0.001
Weight (kg) 0.97 (0.95, 0.99) 0.001
Body surface area (m2) 0.29 (0.15, 0.59) 0.001
Glenn surgery history (yes vs. no) 1.44 (0.96, 2.17) 0.074
Surgeons (senior vs. junior) 1.43 (0.95, 2.15) 0.081
Original anatomy
(Unbalanced AVSD as Ref.)
   Tricuspid atresia 0.52 (0.29, 0.94) 0.03
   Unbalanced DORV 0.9 (0.51, 1.57) 0.703
   Double inlet ventricle 0.45 (0.2, 1.05) 0.065
   Pulmonary atresia 1.7 (0.84, 3.46) 0.139
   TGA 1.01 (0.41, 2.5) 0.983
   CCTGA 1.14 (0.53, 2.42) 0.74
   Others 0.91 (0.27, 3.06) 0.878
Main ventricle ejection fraction (>55% vs. ≤55%) 0.8 (0.46, 1.18) 0.15
Preoperative lymphocyte (× 109/L) 1.1 (0.98, 1.24) 0.102
Preoperative hemoglobin (g/dL) 0.9 (0.84, 0.97) 0.003
Preoperative platelet (× 1010/L) 1.04 (1.02, 1.06) 0.001
Preoperative prothrombin time (s) 0.89 (0.77, 1.02) 0.084
Preoperative alamine aminotransferase (U/L) 0.97 (0.95, 0.998) 0.028
Preoperative aspartate aminotransferase (U/L) 1.03 (1.01, 1.05) 0.01
Preoperative CKMB (U/L) 1.02 (1.01, 1.03) 0.038
Creaction of fenestraion 0.43 (0.29, 0.64) 0.001 0.51 (0.33, 0.79) 0.003
Maximal VIS during surgery 1.03 (1.01, 1.05) 0.027
Intraoperative fluid balance (mL/kg) 1.01 (0.98, 1.013) 0.075
Lactic acid (mmol/L) 1.1 (0.98, 1.25) 0.113
Postoperative lymphocyte (× 109/L) 1.44 (1.11, 1.87) 0.007
Postoperative hemoglobin (g/dL) 0.92 (0.85, 0.99) 0.021
Postoperative platelet (× 1010/L) 1.01 (1.002, 1.03) 0.084
Postoperative prothrombin time (s) 1.09 (1.02, 1.17) 0.005
Postoperative total protein (g/L) 0.96 (0.94, 0.98) 0.001 0.96 (0.93, 0.99) 0.024
Postoperative albumin (g/L) 0.97 (0.94, 0.997) 0.044
Postoperative alamine aminotransferase (U/L) 1.0008 (1.0002, 1.0015) 0.003
Postoperative aspartate aminotransferase (U/L) 1.0007 (1.0002, 1.0013) 0.001
Postoperative TBIL (≥38 vs. <38 μmol/L) 0.72 (0.49, 1.06) 0.093
Postoperative lactate dehydrogenase (U/L) 1.0006 (1.0002, 1.001) 0.002
Postoperative high-sensitivity
C-reactive protein (mg/L)
0.95 (0.89, 1.02) 0.137
Postoperative fluid balance (mL/kg) 1.0036 (0.9993, 1.008) 0.072
Postoperative mechanical ventilation (≥48 vs. <48 h) 2.66 (1.58, 4.46) 0.001 2.52 (1.35, 4.73) 0.004
Chylothorax (yes vs. no) 2.95 (1.98, 4.41) 0.001 2.6 (1.7, 3.98) <0.001

OR, odds ratios; AVSD, atrioventricular septal defect; DORV, double outlet right ventricle; TGA, complete transposition of great arteries; CCTGA, congenitally corrected transposition of the great arteries; CKMB, isoenzyme of creatine kinase-MB; VIS, maximum vasoactive-Inotropic score during surgery; TBIL, total bilirubin. Bold values mean statistical p < 0.05.