Table 5.
Univariate and multivariate Cox analysis hazard ratios for duration of pleural effusions.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95%CI) | p | HR (95%CI) | p | |
| Age at operation (yrs) | 0.96 (0.95, 0.97) | <0.001 | 0.95 (0.93, 0.96) | <0.001 |
| Weight (kg) | 0.98 (0.98, 0.99) | <0.001 | ||
| Body surface area (m2) | 0.49 (0.37, 0.64) | <0.001 | ||
| Admission SpO2 (≥80 vs. <80%) | 1.14 (0.95, 1.36) | 0.147 | ||
| Glenn surgery history (yse vs. no) | 1.45 (0.94, 2.22) | 0.094 | ||
| Original anatomy (Unbalanced AVSD as Ref.) | ||||
| Tricuspid atresia | 0.83 (0.65, 1.06) | 0.140 | ||
| Unbalanced DORV | 1.09 (0.84, 1.41) | 0.52 | ||
| Double inlet ventricle | 0.68 (0.49, 0.95) | 0.02 | ||
| Pulmonary atresia | 1.43 (1.001, 2.04) | 0.049 | ||
| TGA | 1.02 (0.67, 1.54) | 0.95 | ||
| CCTGA | 0.93 (0.65, 1.33) | 0.7 | ||
| Others | 0.87 (0.5, 1.51) | 0.62 | ||
| Main ventricle ejection fraction (>55% vs. ≤55%) | 0.91 (0.71, 1.18) | 0.14 | 0.69 (0.54, 0.90) | 0.006 |
| Preoperative hemoglobin (g/dL) | 0.95 (0.92, 0.98) | 0.001 | ||
| Preoperative platelet (× 1010L) | 1.02 (1.01, 1.03) | 0.000 | ||
| Preoperative prothrombin time (s) | 0.95 (0.91, 0.99) | 0.018 | ||
| Preoperative alamine aminotransferase (U/L) | 0.99 (0.98, 0.9995) | 0.038 | ||
| Preoperative aspartate aminotransferase (U/L) | 1.02 (1.01, 1.03) | 0.003 | ||
| Preoperative TBIL (≥38 vs. <38 μmol/L) | 0.71 (0.48, 1.04) | 0.076 | ||
| Preoperative isoenzyme of creatine kinase-MB (U/L) | 1.01 (1.001, 1.02) | 0.019 | ||
| CPB time (min) | 0.999 (0.998, 1.0003) | 0.142 | ||
| Clamp time (min) | 0.998 (0.996, 1.0001) | 0.058 | ||
| Creaction of fenestraion | 0.59 (0.49, 0.71) | 0.000 | 0.62 (0.52, 0.74) | <0.001 |
| Maximal VIS during surgery | 1.01 (0.999, 1.023) | 0.061 | ||
| Intraoperative fluid balance (mL/kg) | 1.002 (0.999, 1.005) | 0.146 | ||
| Postoperative pulmonary artery pressure (mmHg) | 1.02 (0.99, 1.07) | 0.141 | ||
| Postoperative lymphocyte (× 109/L) | 1.2 (1.06, 1.36) | 0.005 | ||
| Postoperative hemoglobin (g/dL) | 0.96 (0.93, 0.99) | 0.006 | ||
| Postoperative total protein (g/L) | 0.98 (0.97, 0.995) | 0.006 | 0.98 (0.97, 0.99) | 0.038 |
| Postoperative albumin (g/L) | 0.99 (0.97, 1.003) | 0.114 | ||
| Postoperative alamine aminotransferase (U/L) | 1.0002 (1.0001, 1.001) | 0.111 | ||
| Postoperative aspartate aminotransferase (U/L) | 1.0002 (1.0001, 1.001) | 0.076 | ||
| Postoperative alkaline phosphatase | 0.99 (0.98, 1.002) | 0.12 | 0.994 (0.98, 0.998) | 0.037 |
| Postoperative TBIL (≥38 vs. <38 μmol/L) | 0.84 (0.7, 0.996) | 0.045 | ||
| Postoperative lactate dehydrogenase (U/L) | 1.0002 (1.0001, 1.001) | 0.030 | ||
| Postoperative high-sensitivity C-reactive protein (mg/L) | 0.97 (0.95, 1.002) | 0.064 | ||
| Postoperative fluid balance (mL/kg) | 1.001 (1.0001, 1.002) | 0.032 | ||
| Postoperative mechanical ventilation (≥48 vs. <48 h) | 1.5 (1.17, 1.94) | 0.002 | 1.57 (1.17, 2.09) | 0.002 |
| Chylothorax (yes vs. no) | 1.88 (1.57, 2.24) | <0.001 | 1.73 (1.44, 2.08) | <0.001 |
HR, hazard ratios; Admission SpO2, peripheral oxygen saturation when inhaling air; AVSD, atrioventricular septal defect; DORV, double outlet right ventricle; TGA, complete transposition of great arteries; CCTGA, congenitally corrected transposition of the great arteries; CPB, cardiopulmonary bypass; VIS, vasoactive-Inotropic score during surgery; TBIL, total bilirubin. Bold values mean statistical p < 0.05.