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. 2019 Nov 7;10:2577. doi: 10.3389/fimmu.2019.02577

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Copyright © 2019 Lian, Zhang, Zhao, Chen, Peng, Wang, Chen and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cellular identification of IL35 receptor gp130 and IL-12Rβ2 in AIH. Confocal microscopy results showed the colocalization of MDSCs marker CD33 with gp130 (A) and IL-12Rβ2 (B) using the liver tissue of AIH patients. Representative flow cytometric results of gp130 (C) and IL-12Rβ2 (D) on MDSCs showed a substantial abundance of p35 and EBI3 receptor expression in AIH, though no significant difference was observed between AIH and controls. (E) Representative flow cytometric results of IL-27RA on MDSCs from HC and AIH. The average expression of p28 receptor (IL-27RA) was all <10% regardless of disease differences.