Table 2.
Bivariate analysis using categorical testosterone levels within the PCOS cohort.
| High testosterone (n = 38) | Normal testosterone (n = 36) | p value | N | |||
|---|---|---|---|---|---|---|
| Mean ± SD age (range) | 32.4 ± 8.2 | (14.9–57.0) | 39.7 ± 13.8 | (13.63–73.69) | 0.008 | 74 |
| Mean ± SD kg/m2 BMI (range) | 34.3 ± 7.0 | (21.0–54.5) | 27.9 ± 6.3 | (17.93–48.79) | <0.001 | 74 |
| Mean ± SD 24 hr urine panel (range) | ||||||
| Calcium (mg/day) | 223.7 ± 158.5 | (35.5–913.6) | 198.3 ± 87.7 | (50.5–366.7) | 0.426 | 65 |
| Citrate (mg/day) | 709.6 ± 411.7 | (118–1903) | 517.1 ± 257.9 | (82–956 | 0.041 | 54 |
| Creatinine (g/day) | 1.3 ± 0.5 | (0.6–3.2) | 1.2 ± 0.3 | (0.6–1.6) | 0.224 | 56 |
| Oxalate (mg/day) | 37.6 ± 12.3 | (17–66) | 39.3 ± 18.3 | (19–113) | 0.681 | 58 |
| Sodium (mmol/day) | 144.4 ± 54.1 | (49–282) | 123.8 ± 47.8 | (52–283) | 0.154 | 52 |
| Uric acid (mg/day) | 565.3 ± 225.2 | (179–1016) | 461.4 ± 126.9 | (208–739) | 0.028 | 60 |
| Volume (ml/day) | 1721.8 ± 822.9 | (581–3440) | 1561.1 ± 769.6 | (590–3259) | 0.466 | 53 |
| No. abnormality (%) | ||||||
| Hypercalciuria (>200 mg/day) | 17 | (51.5%) | 18 | (56.3%) | 0.893 | 65 |
| Hypocitraturia (<550 mg/day) | 11 | (36.7%) | 13 | (54.2%) | 0.312 | 54 |
| Hyperoxaluria (>40 mg/day) | 13 | (41.9%) | 7 | (25.9%) | 0.316 | 58 |
| Hypernatriuria (>150 mmol/day) | 12 | (40.0%) | 3 | (13.6%) | 0.078 | 52 |
| Hyperuricosuria (>750 mg/day) | 8 | (23.5%) | 0 | (0%) | 0.008 | 60 |
| Low volume (<2000 ml/day) | 17 | (63.0%) | 18 | (69.2%) | 0.848 | 53 |
| Mean ± SD stone composition % (range) | ||||||
| CaOMH | 35.7 ± 31.8 | (0–80) | 59.0 ± 26.0 | (0–90) | 0.062 | 24 |
| CaODH | 16.4 ± 17.8 | (0–60) | 17.5 ± 21.5 | (0–50) | 0.899 | 24 |
| CaPh | 31.4 ± 31.8 | (0–90) | 16.5 ± 23.3 | (0–80) | 0.199 | 24 |
| CaHPh | 7.9 ± 22.3 | (0–80) | — | — | 0.209 | 24 |
| MAP | 4.3 ± 16.0 | (0–60) | — | — | 0.336 | 24 |
| UA | 0.7 ± 2.7 | (0–10) | 3.0 ± 6.8 | (0–20) | 0.332 | 24 |
| No. greater than 70% mixed (%)∗ | 7 | (50%) | 4 | (40%) | 1.000 | 24 |
No adjustments made for confounding variables, original analysis only, and therefore, p values not referenced in discussion. ∗Stones qualified as pure if the dominant component made up ≥70% of the stone.