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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: J Bone Miner Res. 2019 Jul 31;34(11):2087–2100. doi: 10.1002/jbmr.3819

Figure 6: The transcriptional response to mechanical loading is augmented in NT3-Cre+ mice.

Figure 6:

(A) Venn diagram depicting the extensive overlap in DEG lists between Ctrl vs NT3-Cre+ in response to loading (adjusted p-value <0.01). Fold change (expressed as Log2FC) for each genotype and/or loading condition compared to Ctrl NL samples for (B) Wnt genes and (C) other loading-related genes of interest. Significance (adjusted p-value): *p<0.05, #p<0.01, †p<0.001, ‡p<0.0001. Tnfrsf11b (OPG); Tnfrsf11a (RANK); Tnfsf11 (RANKL).