Figure 3. Differential tumor uptake of 64Cu-NOTA-UPSN in different TNBC models.
(A) Whole body MIP from longitudinal PET scans of 4T1 (top panel) and MDA-MB 231 (lower panel) tumor-bearing mice after i.v. injection of 64Cu-NOTA-UPSN. Green arrows indicate the tumors. TACs obtained from in vivo ROI analysis of (B) 4T1 and (C) MDA-MB 231 tumor-bearing mice. (D, E) TACs derived from modeling of the observed data. Data represents mean ± SD (n = 4).