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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Placenta. 2019 Aug 30;87:1–7. doi: 10.1016/j.placenta.2019.08.088

Table 4.

Angiogenesis Multiplex Assay correlated with Cord Blood Alpha Klotho

Biomarker Standardized β-coefficient SE P-Value
Epidermal Growth Factor −0.03 0.07 NS
Angiopoeitin-2 0.64 0.25 0.01
Granulocyte Colony Stimulating Factor 0.02 0.11 NS
Endoglin −0.25 0.19 NS
Endothelin 1 −0.09 0.09 NS
Leptin −0.03 0.09 NS
Fibroblast Growth Factor 1 0.06 0.20 NS
Fibroblast Growth Factor 2 0.08 0.12 NS
Interleukin-8 −0.13 0.15 NS
Hepatocyte Growth Factor −0.03 0.17 NS
Heparin-Binding Epidermal Growth Factor 0.25 0.17 NS
Placental Growth Factor 0.05 0.10 NS
Vascular Endothelial Growth Factor A −0.07 0.07 NS
Vascular Endothelial Growth Factor C 0.03 0.10 NS
Vascular Endothelial Growth Factor D 0.11 0.06 NS

Multiple linear regression was performed in log-transformed variables compared to log-alpha klotho, adjusted for other 14 biomarkers, gestational age, intrauterine growth restriction status, mode of delivery, and preterm labor.