Figure 4. Elevated ET-1 was not associated with impairment in EDR in isolated resistance arteries from overweight/obese humans.
A) Diagram of experimental design and outcomes. Omental adipose tissue resistance arteries were isolated from 29 patients undergoing abdominal surgery. B) Individual vascular and plasma ET-1 concentrations and vasomotor function responses (bradykinin and bradykinin/SNP ratios) for 29 human subjects. C) Correlation of endothelium-dependent relaxation (bradykinin/SNP AUC) with vascular ET-1 content and D) plasma ET-1 concentrations; n=27–29. All data are expressed as individual data points. AUC, area under the curve; NA, data not available.
