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MPAPO promotes cyclin D1, E2F1 protein expression and Rb protein phosphorylation. (A) Western blotting verified the expression of the β-catenin signaling pathway related proteins. (B) MK-2206 inhibits the repair by MPAPO on injured corneal epithelial cells. (C) MK-2206 is able to inhibit the AKT phosphorylation of GSK3β. *P<0.05, **P<0.01, ***P<0.001 compared with the PBS group. #P<0.05, ##P<0.01, ###P<0.001 compared to the NC group. n=3.
