Table 3.
Correlations Between Oxidative Stress Measures of Superoxide (), Catalase (CAT), Superoxide Dismutase (SOD), Reduced Glutathione (GSH), and Oxidized Glutathione (GSSG) Levels at 12−20 Weeks’ Gestation (T1), 24−28 Weeks’ Gestation (T2), Labor (T3), Umbilical Cord at Delivery (T4), and Newborn Infants at 24−72 hr after delivery (NB) in Pregnant Women Receiving Care at a Maternal−Fetal Medicine (MFM) and a General Obstetrics Practice (GOP).
| Oxidative Stress Measure | T1 | T2 | T3 | T4 | NB |
|---|---|---|---|---|---|
| T1 | |||||
| — | MFM (−.221, .21) | MFM (.018, .95) | MFM (−.062, .81) | MFM .053, .75) | |
| GOP (.218, .23) | GOP (−.083, .83) | GOP (−.007, .98) | GOP (−.103, .65) | ||
| CAT | — | MFM (.096, .55) | MFM (.520, <.01) | MFM (.555, <.01) | MFM (.504, .01) |
| GOP (−.109, .45) | GOP (.097, .52) | GOP (.076, .62) | GOP (−.261, .08) | ||
| SOD | — | MFM (.466, .02) | MFM (.269, .10) | MFM (.116, .29) | MFM (.048, .77) |
| GOP (−.148, .30) | GOP (.013, .93) | GOP (−.034, .82) | GOP (−.296, .46) | ||
| GSH | — | MFM (.184, .25) | MFM (.186, .24) | MFM (.003, .99) | MFM (.318, .40) |
| GOP (.200, .172) | GOP (−.133, .38) | GOP (.081, .60) | GOP (.088, .57) | ||
| GSSG | — | MFM (−.552, <.01) | MFM (.057, .73) | MFM (.087, .57) | MFM (−.073, .65) |
| GOP (.127, .39) | GOP (.121, .42) | GOP (−.105, .50) | GOP (−.240, .11) | ||
| T2 | |||||
| MFM (−.221, .21) | — | MFM (−.338, .20) | MFM (−.171, .54) | MFM (−.127, .50) | |
| GOP (.218, .24) | GOP (.600, .29) | GOP (.643, .12) | GOP (−.473, .14) | ||
| CAT | MFM (.096, .55) | — | MFM (.175, .31) | MFM (.096, .56) | MFM (.215, .22) |
| GOP (−.109, .45) | GOP (−.135, .41) | GOP (−.222, .19) | GOP (.034, .84) | ||
| SOD | MFM (.466, .02) | — | MFM (.419, .11) | MFM (.198, .23) | MFM (.291, .09) |
| GOP (−.148, .30) | GOP (−.039, .81) | GOP (.095, .58) | GOP (−.064, .70) | ||
| GSH | MFM (.184, .25) | — | MFM (−.011, .95) | MFM (.046, .78) | MFM (.177, .30) |
| GOP (.200, .17) | GOP (−.506, .01) | GOP (−.114, .52) | GOP (−.143, .41) | ||
| GSSG | MFM (−.552, <.01) | — | MFM (−.249, .14) | MFM (−.290, .07) | MFM (−.203, .23) |
| GOP (.127, .39) | GOP (.417, .09) | GOP (−.031, .86) | GOP (.340, .43) | ||
| T3 | |||||
| MFM (.018, .95) | MFM (−.338, .20) | — | MFM (.718, .13) | MFM (.525, .31) | |
| GOP (−.083, .83) | GOP (.600, .29) | GOP (.200, .80) | GOP (−.900, .37) | ||
| CAT | MFM (.520, <.01) | MFM (.175, .31) | — | MFM (.838, <.01) | MFM (.613, <.01) |
| GOP (.097, .52) | GOP (−.135, .41) | GOP (.421, .07) | GOP (.225, .19) | ||
| SOD | MFM (.269, .10) | MFM (.419, .11) | — | MFM (.164, .31) | MFM (.129, .45) |
| GOP (.013, .93) | GOP (−.039, .81) | GOP (.495, .01) | GOP (.246, .15) | ||
| GSH | MFM (.186, .24) | MFM (−.011, .95) | — | MFM (.653, <.01) | MFM (.501, .01) |
| GOP (−.133, .38) | GOP (−.506, .01) | GOP (.179, .270) | GOP (.264, .12) | ||
| GSSG | MFM (.057, .73) | MFM (−.249, .14) | — | MFM (.835, <.01) | MFM (.295, .065) |
| GOP (.121, .42) | GOP (.417, .09) | GOP (.553, <.01) | GOP (.654, <.01) | ||
| T4 | |||||
| MFM (−.062, .81) | MFM (−.171, .54) | MFM (.718, .13) | — | MFM (.028, .90) | |
| GOP (−.007, .98) | GOP (.643, .12) | GOP (.200, .800) | GOP (.333, .42) | ||
| CAT | MFM (.555, <.01) | MFM (.096, .56) | MFM (.838, <.01) | — | MFM (.686, <.01) |
| GOP (.076, .62) | GOP (−.222, .19) | GOP (.421, .07) | GOP (.175, .32) | ||
| SOD | MFM (.116, .29) | MFM (.198, .23) | MFM (.164, .31) | — | MFM (.326, .03) |
| GOP (−.034, .82) | GOP (.095, .58) | GOP (.495, .01) | GOP (.044, .81) | ||
| GSH | MFM (.003, .99) | MFM (.046, .78) | MFM (.653, <.01) | — | MFM (.209, .16) |
| GOP (.081, .60) | GOP (−.114, .52) | GOP (.179, .27) | GOP (.205, .25) | ||
| GSSG | MFM (.087, .57) | MFM (−.290, .07) | MFM (.835, <.01) | — | MFM (.287, .48) |
| GOP (−.105, .50) | GOP (−.031, .86) | GOP (.553, <.01) | GOP (.412, .16) | ||
| NB | |||||
| MFM (.053, .75) | MFM (−.127, .50) | MFM (.525, .31) | MFM (.028, .90) | — | |
| GOP (−.103, .65) | GOP (−.473, .14) | GOP (−.900, .37) | GOP (.333, .42) | ||
| CAT | MFM (.504, .01) | MFM (.215, .22) | MFM (.613, <.01) | MFM (.686, <.01) | — |
| GOP (−.261, .08) | GOP (.034, .84) | GOP (.225, .19) | GOP (.175, .32) | ||
| SOD | MFM (.048, .77) | MFM (.291, .09) | MFM (.129, .45) | MFM (.326, .03) | — |
| GOP (−.296, .46) | GOP (−.064, .70) | GOP (.246, .15) | GOP (.044, .81) | ||
| GSH | MFM (.318, .40) | MFM (.177, .30) | MFM (.501, .01) | MFM (.209, .16) | — |
| GOP (.088, .57) | GOP (−.143, .41) | GOP (.264, .12) | GOP (.205, .25) | ||
| GSSG | MFM (−.073, .65) | MFM (−.203, .23) | MFM (.295, .65) | MFM (.287, .48) | — |
| GOP (−.240, .11) | GOP (.340, .43) | GOP (.654, <.01) | GOP (.412, .16) | ||
Note. Correlations for oxidative stress measures between each time (T) were analyzed using Spearman’s correlations (rs, p value). Statistically significant correlations (p < .05) after Bonferroni correction are boldfaced.