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. 2019 Oct 7;20(15):1103–1112. doi: 10.2217/pgs-2019-0053

Table 2. . Common medications that may inhibit or induce CYP2C19 or CYP2D6 enzyme activity.

  Inhibitor(s) Inducer(s)
CYP2C19 Strong:
– Fluconazole
– Fluoxetine
– Fluvoxamine

Moderate:
––


Weak:
– Omeprazole
– Voriconazole
Strong:
– Rifampin
– Ritonavir


Moderate:
– Efavirenz
– Phenytoin

Weak:
––
CYP2D6 Strong:
– Bupropion
– Fluoxetine
– Paroxetine

Moderate:
– Cimetidine
– Duloxetine
– Fluvoxamine

Weak:
– Amiodarone
– Celecoxib
– Cimetidine
– Desvenlafaxine
– Escitalopram
– Labetalol
– Ritonavir
– Sertraline
None

Source: FDA, drug development and drug interactions: table of substrates, inhibitors and inducers. Available at: www.fda.gov/Drugs/default.htm (accessed July 24, 2019).