FIG 5.

Impact of reovirus infection on viability of TNBC and L929 cells. MDA-MB-231 (A), MDA-MB-436 (B), and L929 (C) cells were adsorbed with T1L, T3D, T3C$, r1Reovirus, or r2Reovirus at an MOI of 500 PFU/cell or treated with 1 μM staurosporine, and cell viability was assessed at the times shown. Results are presented as MFI and SEM for four independent experiments. The bottom panels show cell viability for all cell lines in panels A to C for days 3, 4, and 1 postinfection. Error bars represent SEM. *, P < 0.01; **, P ≤ 0.001; ***, P ≤ 0.0001 (in comparison to T1L, as determined by two-way ANOVA with Tukey’s multiple-comparison test).