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PCV2 infection induces the phosphorylation and redistribution of lamin A/C mediated by p32. (A, B) p32 knockout promoted the redistribution of lamin A/C and reduced the phosphorylation of lamin A/C. Wild-type PK-15, 173PKp32+/+, and 22PKp32−/− cells were infected with PCV2, and the redistribution of lamin A/C was determined by laser scanning confocal microscopy (A); the phosphorylation levels of lamin A/C were measured by Western blotting (B).
