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. 2019 Oct 31;20(6):4963–4972. doi: 10.3892/mmr.2019.10787

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Effects of a 4-week aerobic exercise regimen. (A) Liver haematoxylin and eosin staining in the control, exercise, HFD and HFD + exercise groups. (B) Corresponding NAS score. The levels of (C) liver injury marker serum ALT (IU/l), and mRNA expression levels of (D) PPARα, (E) ChREBP, (F) liver X receptor and (G) Fsp27 were measured. The mRNA expression data are presented as relative to the control group, which was arbitrarily assigned a value of 100. Data are presented as mean ± standard deviation. *P<0.05, **P<0.01 and ***P<0.001. (H) Muscle oil red O staining (magnification, ×400). HFD, high-fat diet; NAS, non-alcoholic fatty liver disease activity scores; ALT, alanine aminotransferase; PPARα, peroxisome proliferator-activated receptor α; ChREBP, carbohydrate-responsive element-binding protein; Fsp27, fat-specific protein 27.