Skip to main content
. 2019 Oct 9;20(6):5134–5144. doi: 10.3892/mmr.2019.10733

Figure 6.

Figure 6.

Ang II induces the expression of caspase-9 via PI3K/Akt/nuclear factor-κB signaling. Representative reverse transcription-quantitative polymerase chain reaction and western blots of caspase-9 (A) mRNA and (B) protein expression in 10−6 M Ang II-treated podocytes for 48 h are presented. Compared with the control group, Ang II stimulated podocytes to increase the expression of caspase-9 mRNA and protein. #P<0.05 vs. Control. Compared with the Ang II group, the combination of Ang II + 740Y-P decreased the expression of caspase-9 mRNA and protein *P<0.05 vs. Ang II. Ang II + LY294002 increased the expression of caspase-9 mRNA and protein. &P<0.05 vs. Ang II. data are presented as the mean ± standard deviation from three independent experiments. Statistical significance was determined one-way ANOVA. Ang II, angiotensin II.