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. 2019 Oct 23;20(6):4933–4942. doi: 10.3892/mmr.2019.10764

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Copyright: © Deng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Exendin-4 promotes osteogenic differentiation in vitro. (A) Immuno-characterization of FACS-sorted. Sorted cells revealed high expression levels of ADSC-positive markers CD29 and Sca-1 and were negative for CD34 and CD45. (B) In vitro induction of osteogenic differentiation with ADSCs. Magnification, ×200. (C) In vitro induction of adipogenic differentiation with ADSCs. Magnification, ×200. ADSCs, adipose-derived stem cells; OIM, osteoblast-inducing medium; Ex (9–39), an antagonist of exendin-4; AIM, adipose-induced medium.