Table II.
Theaflavin inhibits oxidative stress in NSCs.
| Group | ROS (F/F0) | MDA (mmol/mg) | SOD (U/mg) | GSH-Px (U/mg) |
|---|---|---|---|---|
| Control | 1.21±0.13 | 1.45±0.26 | 16.49±2.36 | 1.52±0.18 |
| OGD/R+ theaflavin (0 mg/kg) | 2.69±0.30a | 2.93±0.34a | 6.38±1.05a | 0.63±0.09a |
| OGD/R + theaflavin (2 mg/kg) | 2.12±0.24a,b | 2.16±0.18a,b | 8.97±1.25a,b | 0.91±0.11a,b |
| OGD/R + theaflavin (10 mg/kg) | 1.64±0.19a–c | 1.74±0.21a–c | 13.26±1.68a–c | 1.34±0.15a–c |
a
P<0.01 vs. the control group
b
P<0.01 vs. the OGD/R + theaflavin (0 mg/kg) group
c
P<0.01 vs. the OGD/R + theaflavin (2 mg/kg) group. NSCs, neural stem cells; OGD/R, oxygen-glucose deprivation and reoxygenation; ROS, reactive oxygen species; MDA, malondialdehyde; GSH-Px, glutathione peroxidase; SOD, superoxide dismutase.