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. 2019 Oct 30;20(6):4953–4962. doi: 10.3892/mmr.2019.10779

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Copyright: © Qin et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Administration of AAV-6-miR-21-5p in lung decreases HALI in rats. Rats were untreated (control), treated with hyperoxia (HALI), or administered with negative control or miR-21-5p-encoding AAV and then treated with hyperoxia. (A) The oxygenation index, (B) respiratory index and (C) wet/dry weight ratio of the lungs were measured in the four experimental groups. Data are expressed as mean ± standard deviation (n=6 rats per group). *P<0.05 with comparisons shown by lines. AAV, adeno-associated virus; miR, microRNA; HALI, hyperoxic acute lung injury.