Table III.
Pathways related to microRNA-132-3p in cholangiocarcinoma.
Geneset | Description | Count | P-value |
---|---|---|---|
WikiPathway | |||
WP143 | Fatty Acid β Oxidation | 5 | 0.002 |
WP3932 | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway | 14 | 0.043 |
WP3972 | PDGFR-β pathway | 3 | 0.046 |
Biological process | |||
GO:0006082 | Organic acid metabolic process | 96 | <0.001 |
GO:0016054 | Organic acid catabolic process | 41 | <0.001 |
GO:0019752 | Carboxylic acid metabolic process | 92 | <0.001 |
GO:0032787 | Monocarboxylic acid metabolic process | 62 | <0.001 |
GO:0043436 | Oxoacid metabolic process | 95 | <0.001 |
GO:0044282 | Small molecule catabolic process | 48 | <0.001 |
GO:0046395 | Carboxylic acid catabolic process | 41 | <0.001 |
GO:0055114 | Oxidation-reduction process | 79 | <0.001 |
GO:0044712 | Single-organism catabolic process | 72 | <0.001 |
GO:0006629 | Lipid metabolic process | 89 | <0.001 |
Cellular component | |||
GO:0005739 | Mitochondrion | 105 | <0.001 |
GO:0044429 | Mitochondrial part | 70 | <0.001 |
GO:0005777 | Peroxisome | 25 | <0.001 |
GO:0042579 | Microbody | 25 | <0.001 |
GO:0005759 | Mitochondrial matrix | 37 | <0.001 |
GO:0044438 | Microbody part | 17 | <0.001 |
GO:0044439 | Peroxisomal part | 17 | <0.001 |
GO:0005782 | Peroxisomal matrix | 10 | <0.001 |
GO:0031907 | Microbody lumen | 10 | <0.001 |
GO:0031966 | Mitochondrial membrane | 38 | <0.001 |
Molecular function | |||
GO:0048037 | Cofactor binding | 42 | <0.001 |
GO:0050662 | Coenzyme binding | 33 | <0.001 |
GO:0016491 | Oxidoreductase activity | 59 | <0.001 |
GO:0016903 | Oxidoreductase activity, acting on the aldehyde or oxo group of donors | 13 | <0.001 |
GO:0000062 | Fatty-acyl-CoA binding | 10 | <0.001 |
GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | 11 | <0.001 |
GO:0098531 | Transcription factor activity, directligand regulated sequence-specific DNA binding | 11 | <0.001 |
GO:0016614 | Oxidoreductase activity, acting on CH-OH group of donors | 17 | <0.001 |
GO:0016620 | Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | 9 | <0.001 |
GO:0008514 | Organic anion transmembrane transporter activity | 19 | <0.001 |
GO, Gene Ontology.