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. 2019 Oct 16;20(6):5197–5207. doi: 10.3892/mmr.2019.10747

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Copyright: © Zhao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 8. — Kae decreases the phosphorylation of 4E/BP1. Relative levels of 4E/BP1 and p-4E/BP1 were detected by western blotting. Treatment with Kae decreased the levels of p-4E/BP1, which was antagonized by Rapa. The data are expressed as the mean ± SEM (n=6 for each group). *P<0.05 vs. respective sham group; ^▲P<0.05 vs. respective OVX group; ^#P<0.05 vs. respective OVX + Kae group. Kae, kaempferol; Rapa, rapamycin; BMSCs, bone mesenchymal stem cells; 4E/BP1, eukaryotic translation initiation factor 4E-binding protein 1; p, phosphorylated; OVX, ovariectomized.