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Effect of PH-EPS on the secretion of IL-1β and TNF-α. RAW 264.7 cells were treated with LPS (1 µg/ml) or the indicated dose of PH-EPS for 1 day. (A) TNF-α and (B) IL-1β levels in the culture media were determined by ELISA. Data are expressed as mean ± standard deviation of 5 replicates. ***P<0.001 vs. UT group. PH-EPS, exopolysaccharides derived from the fungus Paecilomyces lilacinus PH0016; IL, interleukin; TNF, tumor necrosis factor; LPS, lipopolysaccharide; UT, untreated.
