Table III.
Comparisons of the echocardiographic parameters between the subgroups.
| Variables | Compound heterozygous mutations (n=4) | Monoallelic double mutations (n=5) | P-valuea |
|---|---|---|---|
| Age (years) | 32±19 | 40±19 | 0.543 |
| LVOT-PG (mmHg) | 33±28 | 3±2 | 0.123 |
| MLVWT (mm) | 27±3 | 17±8 | 0.068 |
| LA diameter (mm) | 41±6 | 39±11 | 0.079 |
| LVMI (g/m2) | 114±24 | 86±33 | 0.191 |
| LVM (g) | 222±32 | 135±57 | 0.03a |
| LVEF | 64±4 | 61±4 | 0.363 |
| E/A | 1.1±0.3 | 1.0±0.4 | 0.815 |
| E/e′ | 16.57±9.52 | 15.28±10.72 | 0.864 |
| HR (bpm) | 69±12 | 88±21 | 0.157 |
| QRS (msec) | 111±7 | 95±8 | 0.015a |
| PR (msec) | 161±26 | 172±32 | 0.578 |
| QT (msec) | 415±41 | 358±46 | 0.094 |
| QTC (msec) | 440±30 | 424±29 | 0.459 |
| RV5, mV | 1.64±0.67 | 1.00±0.23 | 0.149 |
| SV1, mV | 3.19±1.11 | 1.11±0.38 | 0.028a |
| RV5+SV1, mV | 4.84±1.74 | 2.11±0.56 | 0.047a |
LVOT-PG, left ventricular outflow tract pressure gradient; MLVWT, maximal left ventricular wall thickness; LA, left atrial; LVMI, left ventricular mass index; LVM, left ventricular mass; LVEF, left ventricular ejection fraction; E/A ratio, ratio of early to late mitral inflow velocities; E/e′ ratio, ratio of early diastolic mitral inflow velocity to septal early diastolic mitral annular velocity; HR, heart rate.
a
P<0.05, statistically significant result.