Figure 3.

Intestinal absorptive function was significantly increased in SERTKO animals compared to wild type. (A) Glucose absorption was increased in all regions of the small bowel analyzed, with significant increases in the mid and distal small bowel. (B) Peptide absorption was increased in all regions of the small bowel, with statistically significant increases in the proximal and distal bowel. Overall, these data correlate with our anatomic data, which showed the largest increases in the distal small bowel. All data shown as mean ± SD. *P < 0.05.