Fig. 2.

TMZ-resistant GBM-PDX tumors display increased LC3 II expression. Parental TMZ-sensitive (P) and TMZ-resistant (T) GBM-PDX subcutaneous tumors that were derived from either (a) primary tumor resections or (b) recurrent tumor resections were harvested and lysed for western blot analysis. LC3 protein levels were examined by western blotting and α-tubulin was used as a loading control. c Densitometry was used to quantify the western blot results