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. 2019 Nov 14;18:162. doi: 10.1186/s12943-019-1081-4

Fig. 1.

Fig. 1

Identification of circular RNAs by RNA-seq analyses in GC. (a) RNA-seq analysis of circular RNAs in ten paired human GC tissues and matched normal tissues. (b) Total number of circRNAs and back-spliced reads that were identified in ten paired GC tissues and matched normal tissues. (c) Origin of circRNAs in the genome. (d) Clustered heatmap of the differentially expressed circRNAs in ten paired human GC tissues and matched normal tissues. Rows represent circRNAs, while columns represent tissues. The circRNAs were classified according to the Pearson correlation. (e) Circo plots showing differentially expressed circRNAs and their host genes in GC tissues. Outer: differentially expressed circRNAs; Inner: host genes. The values represent the log (fold change) of cancer vs. normal, red: upregulated, blue: downregulated