Table 1.

Relationship between circLMTK2 expression and clinicopathologic factors of patients with gastric cancer

Parameter	No. of patients	circLMTK2 (high)	circLMTK2 (low)	P -value
Sex				0.871
male	67	35	32
female	53	26	27
Age (year)				0.965
< 60	46	24	22
≥ 60	74	37	37
Tumor site				0.681
Upper	26	12	14
Middle	35	17	18
Lower	47	24	23
Diffuse	12	8	4
Tumor size (cm)				0.279
< 5	54	24	30
≥ 5	66	37	29
Differentiation grade				0.734
Well-moderate	50	24	26
Poor-undifferentiation	70	37	33
Lauren classification				0.812
Intestinal	58	29	29
Diffuse	37	20	17
Mixed	20	9	11
Uncertain	5	3	2
T stage				0.017*
T1-T3	65	26	39
T4	55	35	20
Lymph node status				0.029*
Negative	56	22	34
Positive	64	39	25
Distant metastasis				0.227
M0	109	53	56
M1	11	8	3
TNM stage				0.004*
I-II	56	20	36
III-IV	64	41	23
Lymphatic invasion				0.446
Negative	51	29	22
Positive	69	32	37
Nervous invasion				0.694
Negative	52	28	24
Positive	68	33	35

The TNM Staging System is based on the tumor (T), the extent of spread to the lymph nodes (N), and the presence of metastasis (M)

* P < 0.05